Spusoft 300300mg
Type:10 Capsules
Generic Name:Erdosteine
Manufacturer:Incepta Pharmaceuticals Ltd.
Price:৳150.00
Indication
Symptomatic treatment of acute exacerbations of, chronic bronchitis, in adults as an expectorant.
Administration
The capsules must be swallowed whole with a glass of water.
Adult Dose
Oral As a mucolytic Adult: 300 mg bid. Max duration: 10 days. Hepatic Failure Since there are no data in patients with severe liver failure, the use of erdosteine is not recommended in these patients. Mild to Moderate Hepatic Failure Dose should be reduced
Renal Dose
Since there are no data in patients with creatinine clearance <25ml/min, the use of erdosteine is not recommended in these patients.
Contraindication
Hypersensitivity to the active substance or to any of the other excipients. Active peptic ulcer.
Mode of Action
Erdosteine contains two sulfhydryl groups, which are freed after metabolic transformation in the liver. The liberated sulfhydryl groups break the disulphide bonds, which hold the glycoprotein fibres of mucus together. This makes the bronchial secretions more fluid and enhances elimination.
Precaution
Pregnancy, lactation.
Side Effect
Epigastralgia, nausea, vomiting, loose stools, spasmodic colitis, headache.
