Prostanor 88mg
Type:10 Capsules
Generic Name:Silodosin
Manufacturer:Popular Pharmaceuticals Ltd.
Price:৳240.00
Indication
Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).
Adult Dose
Benign Prostatic Hyperplasia Adults PO 8 mg once daily with a meal. Hepatic Impairment Mild-to-moderate impairment (Child-Pugh class A or B): Dose adjustment not necessary Severe Impairment: (Child-Pugh class C): Contraindicated (not studied)
Renal Dose
Renal Impairment CrCl <50 mL/min: Dose adjustment not necessary CrCl 30-50 mL/min: 4 mg PO qDay CrCl <30 mL/min: Contraindicated
Contraindication
Hypersensitivity.
Mode of Action
Selectively blocks postsynaptic alpha-1 adrenoreceptors located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.
Precaution
Impaired hepatic & renal function. Start treatment w/ a low dose (2 mg/dose).
Side Effect
>10% Retrograde ejaculation (28%) 1-10% Diarrhea (3%),Headache (2%),Insomnia ((1-2%),Dizziness (3%),Orthostatic hypotension (3%; increased in patients >65 years),Nasopharyngitis (2%),Nasal congestion (2%),Sinusitis (1-2%)
Interaction
Ketoconazole, digoxin.
