Desocort0.25%
Type:20gm tube
Generic Name:Desoximetasone
Manufacturer:Incepta Pharmaceuticals Ltd.
Price:৳150.00
Indication
Corticosteroid-responsive dermatoses
Adult Dose
Topical/Cutaneous Corticosteroid-responsive dermatoses Adult: As 0.05-0.25% cream/gel/lotion/oint: Apply a thin film onto affected area bid. Rub in gently.
Child Dose
Topical/Cutaneous Corticosteroid-responsive dermatoses Child: As 0.05-0.25% cream/gel/lotion/oint: Apply a thin film onto affected area bid. Rub in gently.
Contraindication
Hypersensitivity
Mode of Action
Desoximetasone is a topical corticosteroid that induces phospholipase A2 inhibitory proteins (lipocortins) and sequentially inhibits the release of arachidonic acid hence depresses the formation, release, and activity of endogenous chemical mediators such as kinins, histamine, liposomal enzymes, and prostaglandins.
Precaution
Childn. Pregnancy and lactation. Patient Counselling Avoid use of occlusive dressings. Topical spray is flammable, avoid exposure to heat and flame or smoking during or immediately after application. Monitoring Parameters Monitor for hypothalamic-pituitary-adrenal (HPA) axis suppression through ACTH stimulation or urinary free cortisol test.
Side Effect
Frequency Not Defined Skin atrophy Striae Acneform lesions Pruritus Irritation Miliaria Folliculitis Erythema Hypopigmentation Vesiculation Pigmentation changes HPA suppression (with higher potency used >2 wk)
Pregnancy Category Note
Pregnancy Category: C Lactation: excretion in milk unknown; use with caution
Interaction
May diminish the antineoplastic effect of aldesleukin. May potentiate the hyperglycaemic effect of ceritinib. May diminish the therapeutic effect of corticorelin and hyaluronidase. May enhance the adverse/toxic effects of deferasirox.
