Konakion2mg/0.2ml
Type:1 amps
Generic Name:Phytomenadione (Vitamin K1)
Manufacturer:Roche Bangladesh Pharmaceutical
Price:৳98.00
Indication
Vitamin K deficiency, Over-anticoagulation, Vitamin K deficiency bleeding
Administration
May be taken with or without food.
Adult Dose
Oral Vitamin K deficiency due to drugs or malabsorption Adult: 10-40 mg daily. Over-anticoagulation Adult: Up to 5 mg may be used. Dose depends on INR and degree of haemorrhage. Intravenous Over-anticoagulation Adult: 0.5-5 mg via slow IV inj. Dose depends on INR and degree of haemorrhage.
Child Dose
Intramuscular Prophylaxis of vitamin K deficiency bleeding in neonates Child: Neonate: 0.5-1 mg, given as a single dose via IM inj. Alternatively, 2 mg may be given orally, followed by a 2nd dose of 2 mg after 4-7 days. Parenteral Vitamin K deficiency bleeding in neonates Child: Infant: 1 mg by IV/IM/SC inj, further doses may be given if necessary
Contraindication
Hypersensitivity.
Mode of Action
Phytomenadione promotes hepatic synthesis of clotting factors. It is a naturally occurring compound that is used to prevent and treat haemorrhages related to vitamin K deficiency.
Precaution
Increased risk of severe haemolytic anaemia in neonates after large doses; severe hepatic impairment; pregnancy. Premature neonates weighing <2.5 kg. Lactation: Excreted in breast milk; use caution
Side Effect
Anaphylaxis, dyspnoea, cyanosis, pain, swelling, phloebitis at the Inj site, diaphoresis, dizziness, hypotension (rare), allergic reactions after SC and IM inj.
Interaction
Decreased effect of oral anticoagulants.
