Zilapro 250250mg
Type:Capsule
Generic Name:Cefprozil
Manufacturer:Beximco Pharmaceuticals Ltd.
Price:৳30.00
Indication
Pharyngitis, Susceptible infections, Sinusitis, Otitis media, Skin and skin structure infections, Tonsillitis, Respiratory tract infections, Acute Maxillary Sinusitis, Acute bacterial exacerbation of chronic bronchitis
Administration
May be taken with or without food. May be taken w/ meals to reduce GI discomfort.
Adult Dose
Pharyngitis & Tonsillitis 500 mg PO qDay for 10 days Respiratory Tract Infections, Skin Infections 250-500 mg q12hr OR 500 mg qDay for10 days
Child Dose
Child: PO 15–30 mg/kg/day q12h
Renal Dose
Renal impairment: CrCl (ml/min) <30 Half normal dose.
Contraindication
Hypersensitivity.
Mode of Action
Cefprozil inhibits cell wall synthesis and has activity against a broad range of gram-positive and gram-negative bacteria.
Precaution
Hypersensitivity to penicillins; renal impairment; porphyria. Monitor renal and haematologic status. Pregnancy, lactation. Lactation: low distribution into breast milk; use with caution
Side Effect
1-10% Nausea (3.5%),Diarrhea (2.9%),Elevated LFTs (2%),Diaper rash (1.5%),Abdominal pain (1%),Dizziness (1%),Vomiting (1%) <1% Eosinophilia,Superinfection,Vaginitis,Cholestatic jaundice,Elevated BUN & creatinine,Prolonged PT Potentially Fatal: Pseudomembranous colitis.
Pregnancy Category Note
Pregnancy Category: B Lactation: low distribution into breast milk; use with caution
Interaction
Renal excretion delayed by probenecid. Decreases contraceptive effect of oestrogen-containing oral contraceptives.