Ocuclor1%
Type:3gm tube
Generic Name:Chloramphenicol 1% Eye prep
Manufacturer:General Pharmaceuticals Ltd.
Price:৳8.52
Indication
Bacterial Conjunctivitis
Adult Dose
Ocular infections Adult: Apply a 1% ointment 3-4 times daily. Hepatic impairment: Dose reduction may be required.
Renal Dose
Renal impairment: Dose reduction may be required.
Contraindication
History of hypersensitivity to the drug; Herpes simplex and other virul conditions of the eye, mycosis.
Mode of Action
Chloramphenicol inhibits bacterial protein synthesis by binding to 50s subunit of the bacterial ribosome, thus preventing peptide bond formation by peptidyl transferase. It has both bacteriostatic and bactericidal action against H. influenzae, N. meningitidis and S. pneumoniae.
Precaution
Avoid prolonged use. Discontinue immediately if local hypersensitivity reactions occur.
Side Effect
Ophthalmic application: Hypersensitivity reactions including rashes, fever and angioedema.
Interaction
Decreased effects of iron and vitamin B12 in anaemic patients. Phenobarbitone and rifampin reduce efficacy of chloramphenicol. Impairs the action of oral contraceptives. Potentially Fatal: Increases the effect of oral anticoagulants, oral hypoglycaemic agents, phenytoin. Avoid concomitant administration with drugs that depress bone marrow function.
Alternative brand of Ocuclor
G Chloramphenicol- 1%
- Eye Ointment
- Chloramphenicol 1% Eye prep
Price: ৳8.00
Gonoshasthaya Pharmaceuticals Ltd.
Supraphen- 1%
- Eye Ointment
- Chloramphenicol 1% Eye prep
Price: ৳12.53
Gaco Pharmaceuticals(G.A Company Ltd)
