Nystat5LacUnit
Type:10 Tablets
Generic Name:Nystatin
Manufacturer:The ACME Laboratories Ltd.
Price:৳62.70
Indication
Fungal infections, Oropharyngeal candidiasis, Intestinal candidiasis, Vaginal candidiasis
Administration
May be taken with or without food.
Adult Dose
Oral Oral candidiasis Adult: As oral susp or drop : 100,000-600,000 U (1-6 ml drop) into the mouth 4 times daily. Keep in contact w/ affected area as long as possible. Continue for 48 hr after clinical cure to prevent relapse. Intestinal candidiasis Adult: As tab or oral susp/drop: 500,000 or 1,000,000 U 3-4 times daily. Prophylaxis: 1,000,000 U daily. Vaginal Vulvovaginal candidiasis Adult: insert 1 vaginal tablet into vagina daily at bedtime for 14 days or longer.
Child Dose
As oral susp or drop Infants: PO: 2 mL/dose, children 4–6 mL/dose, to coat oral mucosa q6h As tab Child: PO: 3–6 tabs/day tid For prophylaxis of oral candidiasis in the newborn the suggested dose is 1 ml (100,000 U) once daily. Administration should be continued for 48 hours after clinical cure to prevent relapse.
Contraindication
Hypersensitivity.
Mode of Action
Nystatin, a polyene antifungal, binds to ergosterol in the fungal cell membrane. This binding affects the cell wall permeability allowing leakage of cellular contents.
Precaution
Immunocompromised patients. Childn. Pregnancy and lactation. Patient Counselling May damage latex contraceptives (vag). Lactation: Not known if excreted in breast milk; use caution
Side Effect
Nausea, vomiting, diarrhoea, GI upset, oral irritation and sensitisation. Rarely, rash, urticaria, Stevens-Johnson syndrome, tachycardia, bronchospasm, facial swelling, nonspecific myalgia Vaginal tablet: May damage latex contraceptives (e.g. diaphragms, condoms), additional contraceptive measures should be taken. Localized sensitization.
Pregnancy Category Note
Pregnancy category: C, ROUTE(S) : Mouth/Throat / PO Pregnancy Category: A, ROUTE(S) : Vaginal
