Indication
Migraine, Vertigo, Peripheral vascular disease, Cerebrovascular disorders, Vestibular disorders
Administration
May be taken with or without food.
Adult Dose
Oral Prophylaxis of migraine; Prophylaxis of vertigo and vestibular disorders; Prophylaxis of peripheral and cerebrovascular disorders Adult: 5-10 mg daily at bedtime.
Contraindication
Pregnancy, lactation, GI or urinary tract obstruction, acute porphyrias.
Mode of Action
Flunarizine has H1-receptor blocking action and calcium-channel blocking effect. It has also been used as an adjunct epileptic therapy for patients refractory to standard treatment regimens.
Precaution
Driving or operating machinery, epilepsy, elderly, CVS disease, glaucoma.
Side Effect
Drowsiness. Rarely wt gain, headache, depression, gastric pain, dry mouth, insomnia, extrapyramidal reactions, galactorrhoea.
Interaction
Plasma levels reduced by phenytoin, carbamazepine, valproic acid.






















