Melphin125mg
Type:Tablet
Generic Name:Pyrantel Pamoate
Manufacturer:Beximco Pharmaceuticals Ltd.
Price:৳1.67
Indication
Enterobiasis, Ascariasis, Worm infections, Trichinosis
Administration
May be taken with or without food.
Adult Dose
Oral Single or mixed infections due to susceptible worms Adult: 10 mg/kg as a single dose. Ascariasis Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr. Necatoriasis Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days. Enterobiasis Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose. Trichinosis Adult: 10 mg/kg daily for 5 days.
Child Dose
<2 years: Safety and efficacy not established Oral Single or mixed infections due to susceptible worms Child: 10 mg/kg as a single dose.
Contraindication
Hypersensitivity
Mode of Action
Pyrantel is effective against roundworms (Ascaris), threadworms (Enterobius), hookworms and Trichostrongylus. Not effective against whipworm. Acts by paralysing the worms which get detached and are excreted by intestinal peristalsis.
Precaution
Liver dysfunction, anaemia or severe malnutrition. Treat members in close contact with the patient.
Side Effect
Anorexia, nausea, vomiting, abdominal cramps, drowsiness, insomnia, diarrhoea, tenesmus, SGOT elevations, headache, dizziness, rash.
Interaction
Potentially Fatal: Mutually antagonistic with piperazine.
