
Matropin2gm/100ml
Type:10ml drop
Generic Name:Homatropine Hydrobromide Eye prep
Manufacturer:Aristopharma Limited
Price:৳56.70
Indication
Mydriasis and cycloplegia for refraction, Dilatation of pupil
Adult Dose
Ophthalmic Mydriasis and cycloplegia for refraction Adult: Instill 1 or 2 drops of 2% solution, may repeat at 10-15 min intervals if necessary; not to exceed 5 doses Uveitis Adult: Instill 1-2 drops of 2% bid-tid up to every 3-4 hr as needed.
Child Dose
Ophthalmic Mydriasis and cycloplegia for refraction Child: Instill 1 drop of 2% soln immediately before the procedure, repeat at 10-min intervals if necessary. Uveitis Child: >2 yr: instill 1 drop of 2% soln bid.
Contraindication
Acute haemorrhage; narrow-angle glaucoma; primary glaucoma; predisposition to glaucoma; hypersensitivity.
Mode of Action
Homatropine, a tertiary amine antimuscarinic, produces dilation and loss of accommodation by blocking the response of iris sphincter muscle and the accommodative ciliary muscle to cholinergic stimulation.
Precaution
Hypertension; cardiac disease; unstable CV status in acute haemorrhage; increased intraocular pressure; obstructive uropathy; paralytic ileus; ulcerative colitis; elderly; infants; young child; pregnancy. Finger pressure should be applied on the lachrymal sac for 1-2 minutes after instillation to reduce systemic absorption. Lactation: Excretion in milk unknown; not recommended
Side Effect
Blurred vision; photophobia; increased intraocular pressure. Prolonged use may cause local irritation characterized by follicular conjunctivitis, vascular congestion, oedema, exudate and eczematoid dermatitis.
Interaction
Effects may be increased by drugs with antimuscarinic effect such as; some antihistamines; phenothiazines; antipsychotics; TCAs; MAOIs or parasympathomimetics.


