Fucidin
Type:Tablet
Generic Name:Sodium Fusidate (Fusidic Acid)
Manufacturer:Leo Pharmaceutical Products, Denmark
Price:৳120.00
Indication
Acne vulgaris, Skin infections, Conjunctivitis, staphylococcal infections
Administration
Should be taken with food.
Adult Dose
Oral Susceptible infections Adult: 500 mg tid. May increase to 1 g tid in fulminating infections.
Child Dose
Oral Susceptible infections Child: <1 yr: About 15 mg/kg; 1-5 yr: 250 mg; 5-12 yr: 500 mg. Doses to be taken tid.
Contraindication
Hypersensitivity.
Mode of Action
Fusidic acid disrupts translocation of peptide subunits and elongating the peptide chain of susceptible bacteria, thus inhibiting protein synthesis.
Precaution
Hepatic disease; monitor liver function. Neonates; pregnancy, lactation.
Side Effect
Jaundice and liver dysfunction (reversible); GI disturbances. IV: Venospasm, thrombophloebitis and haemolysis; hypocalcaemia. SC/IM: Tissue necrosis. Topical: Rashes and irritation.
Interaction
Synergistic action with antistaphylococcal penicillin. Antagonism with ciprofloxacin.
