Fexomin 180180mg
Type:10 Tablets
Generic Name:Fexofenadine Hydrochloride
Manufacturer:The Ibn Sina Pharmaceutical Ind. Ltd.
Price:৳90.00
Indication
Allergic rhinitis, Hay fever, Urticaria, Allergy
Administration
Should be taken on an empty stomach. Take before meals. Do not take w/ fruit juice.
Adult Dose
Adults: Allergic rhinitis: 120 mg once daily or 60 mg twice daily Urticaria: 180 mg once daily
Child Dose
Children: Tablet 2-12 years: 30 mg (1 spoonful) or 5 ml twice daily 6 months-2 years: 15 mg (1/2 spoonful) or 2.5 ml twice daily >12 years: 60 mg PO BID OR 180 mg PO qDay ODT 6-12 years: 30 mg PO BID
Renal Dose
Adult: Initially, 60 mg once daily. Child: 6 mth-<2 yr: 15 mg once daily and 2-11 yr: 30 mg once daily. >12 years: 60 mg PO qDay, initially
Contraindication
Hypersensitivity.
Mode of Action
Fexofenadine, an active metabolite of terfenadine, is a competitive peripheral histamine H1-receptor antagonist on effector cells in the GI tract, blood vessels and respiratory tract.
Precaution
Renal impairment. Pregnancy, lactation; children <6 yr. Lactation: Excretion in milk unknown; use with caution (AAP states “compatible with nursing”)
Side Effect
>10% Vomiting (6-12%) 1-10% Headache (5-10%),Cough (4%),Diarrhea (3-4%),URTI (3%),Back pain (2-3%),Pyrexia (2%),Dysmenorrhea (2%),Dizziness (2%),Stomach discomfort (2%),Pain in extremity (2%),Somnolence (1-3%),Rhinorrhea (1-2%)
Pregnancy Category Note
Pregnancy category: C Lactation: Excretion in milk unknown; use with caution (AAP states “compatible with nursing”)
Interaction
Co-admin with ketoconazole or erythromycin may increase plasma levels of fexofenadine. May increase adverse effects of other anticholinergics and CNS depressants. May increase arrhythmogenic effect of antipsychotic agents (phenothiazines); avoid concurrent usage. May reduce the efficacy of betahistine. Pramlintide may increase the anticholinergic effect of fexofenadine. Bioavailability may be increased by verapamil. Efficacy may be reduced by rifampin.
