Etomid2mg/ml
Type:Injection
Generic Name:Etomidate
Manufacturer:Popular Pharmaceuticals Ltd.
Price:৳150.00
Indication
Anaesthesia
Administration
IV Administration Inject undiluted by direct IV injection over 30-60 sec; do not administer by prolonged IV infusion Inject into large forearm vein
Adult Dose
General Anesthesia Induction 0.3-0.6 mg/kg IVP over 30-60 sec
Child Dose
General Anesthesia Induction <10 years: Safety and efficacy not established >10 years: 0.3-0.6 mg/kg IVP over 30-60 sec
Contraindication
Hypersensitivity. Reduced or at risk of reduced adrenocortical function. Porphyria.
Mode of Action
Etomidate is a carboxylated imidazole. It is a sedative and hypnotic agent used commonly for induction anaesthesia.
Precaution
Opioid analgesics or benzodiazepines may be given as premedications to reduce risk of convulsions. Not to be admin by prolonged infusion. Pre-existing epilepsy. Elderly and child <10 yrs. Pregnancy and lactation. Lactation: Not known if excreted in breast milk; use caution
Side Effect
>10% Transient injection site pain (30-80%),Skeletal muscle movements, mainly myoclonic (32%),Opsoclonus (20%),Adrenal suppression 1-10% Hiccups <1% Apnea (duration: 5-90 seconds),Arrhythmias,Hyperventilation,HTN,Hypotension,Hypoventilation,Laryngospasm,Nausea/vomiting,Oxygen desaturation,Snoring (may be associated with partial upper airway obstruction)
Pregnancy Category Note
Pregnancy category: C Lactation: Not known if excreted in breast milk; use caution
Interaction
Antipsychotics, sedatives or opioids; calcium-channel blockers.