Medicase - Cortefin - 10gm tube - 0.10% - Triamcinolone Acetonide 0.1% Topical

Cortefin0.10%

Type:10gm tube

Generic Name:Triamcinolone Acetonide 0.1% Topical

Manufacturer:ACI Limited

Price:৳25.08

Indication

Inflammatory skin conditions

Adult Dose

Topical/Cutaneous Inflammatory skin conditions Adult: Apply cream/ointment sparingly onto affected area 2-3 times daily.

Child Dose

Topical/Cutaneous Inflammatory skin conditions Adult: Apply cream/ointment sparingly onto affected area 2-3 times daily.

Contraindication

Untreated systemic fungal, bacterial, viral or parasitic infection, hypersensitivity.

Mode of Action

Triamcinolone has mainly glucocorticoid activity. It suppresses the migration of polymorphonuclear leukocytes and reduces capillary permeability thereby decreasing inflammation.

Precaution

Diabetes; hypertension, renal and liver impairment; glaucoma; psychosis; delayed tissue healing; cirrhosis; heart failure; recent MI; hypothyroidism; osteoporosis; peptic ulceration; thromboembolic disorders. Monitor height in children on prolonged therapy. Avoid rapid drug withdrawal. Elderly, children, pregnancy, lactation.

Side Effect

Skin atrophy, Striae, Acneform lesions, Pigmentation changes, HPA suppression (with higher potency used >2 weeks)Systemic absorption if applied to large areas, broken skin or under occlusive dressing.

Interaction

Lowering of plasma salicylates levels. Increased risk of GI bleeding and ulceration with NSAIDs. Antagonised blood glucose-lowering effects of the antidiabetics. Increased risk of hyperkalaemia with amphotericin B, beta agonists, beta-blockers, potassium-depleting diuretics, theophylline. Increased clearance of the triamcinolone with ciclosporin, carbamazepine, phenytoin, barbiturate, rifampicin. Infections may develop if given with live vaccines.